Decentralized sanitation, where infrastructure doesn't reach
Fecal sludge, septage, and biosolids in low-resource or cold-climate contexts where centralized wastewater treatment is not available, not viable, or not cost-effective to extend. The problem is geography and population density making sewage infrastructure economically irrational. Arctic communities in Alaska, peri-urban settlements in India, off-grid industrial camps. The Biogenic Refinery's founding mission — under the Bill & Melinda Gates Foundation Reinvent the Toilet Challenge — was exactly this category.